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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XDH
All Species:
37.58
Human Site:
S406
Identified Species:
82.67
UniProt:
P47989
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P47989
NP_000370.2
1333
146424
S406
S
P
E
E
I
L
L
S
I
E
I
P
Y
S
R
Chimpanzee
Pan troglodytes
XP_525729
1333
146376
S406
S
P
E
E
I
L
L
S
I
E
I
P
Y
S
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540143
1333
147201
S407
A
P
E
E
I
L
L
S
I
E
I
P
Y
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q00519
1335
146500
S408
S
P
E
E
I
L
V
S
I
V
I
P
Y
S
R
Rat
Rattus norvegicus
P22985
1331
146224
S405
R
P
E
E
I
L
L
S
I
E
I
P
Y
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509432
1297
142673
S406
S
P
Q
E
I
L
L
S
I
E
I
P
Y
S
Q
Chicken
Gallus gallus
P47990
1358
149595
S432
K
P
E
E
V
L
L
S
V
E
I
P
Y
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688983
1351
148155
S423
K
P
E
E
I
L
L
S
I
E
I
P
Y
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10351
1335
146909
G408
E
A
H
E
V
L
L
G
I
H
F
R
K
T
T
Honey Bee
Apis mellifera
XP_001119950
1356
152206
S439
S
S
E
E
I
L
L
S
I
Q
I
P
F
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7G192
1321
144562
S396
E
A
H
D
L
V
L
S
I
E
I
P
F
W
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.4
N.A.
89.1
90.3
N.A.
70.4
72.3
N.A.
67.8
N.A.
52.6
52.4
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
95.4
N.A.
95.1
95.8
N.A.
82.3
84
N.A.
81.4
N.A.
69.5
70.5
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
86.6
73.3
N.A.
80
N.A.
26.6
73.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
100
93.3
N.A.
93.3
N.A.
40
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
73
91
0
0
0
0
0
73
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
19
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
19
0
0
0
0
0
0
10
0
0
0
0
10
% H
% Ile:
0
0
0
0
73
0
0
0
91
0
91
0
0
0
0
% I
% Lys:
19
0
0
0
0
0
0
0
0
0
0
0
10
0
28
% K
% Leu:
0
0
0
0
10
91
91
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
73
0
0
0
0
0
0
0
0
0
91
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
37
% R
% Ser:
46
10
0
0
0
0
0
91
0
0
0
0
0
73
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
10
% T
% Val:
0
0
0
0
19
10
10
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _